Hepatitis B drug after another, such as hospital preparation, research and medicine, Chinese medicine in the Wan San paste Dan and various kinds of “secret prescription,” dazzled people. Hepatitis B drug in so many should be how to choose? Effect of what?

Efficacy of hepatitis B in accordance with their regular medication can be broadly divided into: general hepatoprotective drugs, Hugan restore liver function drugs, antiviral drugs, immunomodulatory drugs, anti-hepatic fibrosis drugs and proprietary Chinese medicines and other six major categories.

General Liver drugs include a variety of vitamins, the liver was Jian, Glucurolactone etc., applicable to all types of hepatitis and cirrhosis of the liver, but may only play a secondary and indirect effects. These drugs can reduce inflammation of the liver and promote liver regeneration, but not the protagonist of hepatitis B treatment.

Liver restore liver function and the longest study of drugs such drugs, efficacy of the most clear, the most widely used, the price is relatively low, including Hugan JiangMei, Hugan drop yellow and Liver protein metabolism in three types of improvements. They are applicable to various types of hepatitis, cirrhosis of the liver appeared aminotransferase, bilirubin increase or decrease albumin and protein ratio of upside-down, etc., which Hugan JiangMei drugs are the most widely used, the most prominent effect of a class of drugs, such as Gomi son, licorice preparations. Clinical hepatitis B patients seen, almost all accompanied by elevated transaminase this phenomenon, under normal circumstances, the use of drugs can be received Hugan JiangMei immediate effect. Although these drugs JiangMei quickly, but not a sudden withdrawal, or transaminase quickly “anti-jump”, a gradual reduction should be to maintain a year or two.

Liver lowering drugs for Huang hepatitis and cirrhosis of the liver in all patients with elevated bilirubin (ie, jaundice), such as western aspartic acid potassium, ursodeoxycholic acid and traditional Chinese medicine Danshen injection agent. One drop Western Huang mainly applicable to accompanied by the characteristics of cholestatic hepatitis, Chinese medicine formulations suitable for various types of high-jaundice cases. Lowering drugs in general should not be used for a long yellow, if the chronic hepatitis B and liver cirrhosis a “residual jaundice” phenomenon, we should not use these drugs can be added with the prescription of Chinese herbal medicine to be adjusted to resolve dialectical.

Liver protein metabolism improving drug, amino acids such as oral capsules, Malotilate and so on, mainly applied to chronic hepatitis (generally moderate), or patients with cirrhosis of the liver to reduce albumin, globulin increased, protein ratio of upside-down, lower the price , efficacy can still be. If the later stage of liver cirrhosis with ascites, hypoalbuminemia, which normally takes input human serum albumin, the price is very expensive. Liver drug treatment to restore liver function in clear and obvious, it is regrettable that they are not cure hepatitis B method, they belong to hepatitis B “symptoms” approach (ie, mitigation of hepatitis B method). They can solve some of hepatitis B surface phenomena, such as mitigation of liver inflammation and promote regeneration, etc., but can not resolve the core issue of hepatitis B – anti-virus treatment.

Antiviral drugs, these drugs for mild to moderate chronic hepatitis, early cirrhosis patients, the main indicators of viral replication (e antigen, hepatitis B virus deoxyribonucleic acid)-positive persons are not generally suitable for the treatment of people living with HIV, severe hepatitis and in patients with advanced liver cirrhosis. Hepatitis B antiviral therapy is the treatment of hepatitis B core and key element is the difficulty where the treatment of hepatitis B, it is a “hard bone”, has yet to “bite” down. Treatment of hepatitis B in China at different times have different “main” drugs, such as the western interferon, lamivudine and traditional Chinese medicine Ganyanlin so on, but the vast majority of anti-viral medicine is a “flash in the pan,” poor efficacy. The 20th century, 90 years, interferon has been solemnly recommend to the nation, at that time was regarded as hepatitis B nemesis, popular for nearly 6-7 years, but due to unsatisfactory efficacy (racial differences, side effects, are expensive and other factors it does not suitable for Chinese people), but also gradually on the decline, replaced by the lamivudine, which is the latest antiviral drugs.

Compared to other western medicine, the lamivudine has many advantages, such as relatively cheap, and side effects, mouth eyes convenient, curb the virus quickly, for the hepatitis B virus DNA (HBV-DNA) negative rate of up to 90 %, and for hepatitis B virus e antigen (HBeAg) of the negative conversion rate was more than 40% and so on and therefore I was all the rage. However, lamivudine is not a magic pill, it does not completely solve the problem of hepatitis B, such as after stopping the “rebound,” within the foreseeable future course of treatment, the virus under drug pressure variation, long-term efficacy is inconclusive and so on . Lamivudine treatment of hepatitis B is also a milestone in the journey, but by no means the end of the treatment of hepatitis B. Many types of antiviral drugs, traditional Chinese medicine, its advantages are cheap, side effects and so on, but Western medicine is relatively speaking, the effectiveness of anti-virus is not enough, the mechanism is not clear, therefore, difficult to solely responsible for hepatitis B “main role.”

Immunomodulatory drugs, including two types of immune enhancer and immune inhibitors. Immunostimulants can enhance cellular immune function and induce endogenous interferon production, the promotion of hepatitis B virus antigen was negative indicators. In addition, some traditional Chinese medicines have their effect. Objectively speaking, preparation is still a hepatitis B immunization adjuvant therapy, but it was too expensive adjuvant therapy, the immune enhancer premium is very high, high level has been more than antiviral drugs, which makes a little “forest for the trees” feeling. Immunosuppressive agents can be used to cholestatic hepatitis, autoimmune hepatitis and severe hepatitis, but the effect is not accurate, anti-viral effect is paradoxical, therefore not worth advocating.